VAP Bundle Ventilator Associated Pneumonia Ventilator Associated Pneumonia ( VAP) is a lung infection that occurs in patients who are on mechanical ventilation for more than 48 hours. A VAP bundle is a set of Preventing Ventilator Associated Infections Intubation and VAP: Complex Condition, Bundled Solutions RT Trial: Inhaled preventive antibiotic reduces risk of ventilator associated pneumonia CIDRAP VAP = Ventilator Associated Pneumonia Think it in any ventilated patient with: Fever Purulent secretions New infiltrate on CXR Worsening oxygenation Prevention Head elevation vap intubation Main endogenous and exogenous risk factors for VAP